University of Toronto St. George Campus - Statistics
Postdoctoral training
Bioinformatics
The Ohio State University
Doctor of Philosophy (Ph.D.)
Statistics
University of Toronto
Master's degree
Statistics
McMaster University
Master's Degree
Mathematics
Hebei Normal University
Developed a pipeline to process bisulfite-treated methylation sequencing data using compiled open-source software
as well as to conduct statistical analysis for bisulfite rate and sequencing structure using custom programs written in Perl and R.
Aaron Noviski
Identify differential methylation in bisulfite sequencing data
1. Developed a Hidden Markov Model based algorithm to identify differential methylations in bisulfite-treated methylation sequencing data with single-CpG resolution. Wrote an R pipeline implementing the algorithm as well as providing downstream analysis
including methylation data visualization and genomic annotation. Applied the algorithm to a case control study of breast cancer. \n\n2. Developed an a new statistical methodology based on Markov Chain Monte Carlo algorithms and fisher-exact test to detect the differentially methylated regions among different cancer conditions using reduced representation bisulfite sequencing data.
Sun
Sun
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