Resume

• 2009

  Sanford School of Medicine

  Sioux Falls

  SD

  Work on lipid and fatty acid metabolism

  especially lipid mediators (oxylipins) and how they relate to risk for cardiovascular and metabolic disease.

  Associate Scientist

  Sanford Research/USD

  110 Chandlee Laboratory

  Lipid mediators are bioactive metabolites of dietary fatty acids. They act on tissues to mediate many disease-related functions

  including the stiffness of blood vessels and the body's response to stress. \n\nMost investigations focus on the actions of individual lipid mediators

  however a major stress from over-nutrition and \"western diets\" is a global shift of dietary fatty acids

  not in any single fatty acid. The consequence of multiple changes in fatty acids is multiple changes in the lipid mediators. We seek to understand disease-related functional changes in the context of globally changed lipid mediators and use them identify markers of disease and better ways to prevent or manage disease.

  Associate Professor

  The Pennsylvania State University

  Sioux Falls

  South Dakota Area

  Sanford School of Medicine

• 2001

  Dept of Veteran's Affairs

  The Pennsylvania State University

  Dept of Veteran's Affairs

• 1994

  PhD

  Physiology

• 1987

  BS

  Biochemistry

• 344

  A method for predicting risk for myocardial infarction using the fatty acids comprising red blood cell membranes instead of traditional markers such as age

  blood pressure

  and LDL-cholesterol.

  Fatty acid pattern analysis for predicting acute coronary syndrome

• Immunohistochemistry

  Western Blotting

  In Vivo

  Molecular Biology

  Biochemistry

  PCR

  Microscopy

  Metabolic Syndrome

  Cell Culture

  Lipids

  Genetics

  Lifesciences

  Life Sciences

  ELISA

  Animal Models

  Metabolism

  Cell Biology

  Shearer

  Greg

  Shearer

  Sanford Research/USD