Resume

• 2001

  Doctor of Philosophy (Ph.D.)

  Thesis: Role of Fc Receptor-Like proteins in immune responses. Molecular cloning of two members of the FCRL family

  FCRLB and FCRL6; established FCRL6 as a biomarker for effector and effector-memory T cell expansion during HIV infection;u established FCRL4 as a receptor for IgA and FCRL5 as a receptor for IgG; demonstrated association of FCRLA with intracellular immunoglobulins in B cells; phenotypic characterization of FCRLA deficient mice in normal immune responses and pristane-induced lupus.\n\nAlso: studied in vivo roles of TLR3 and MDA5 function in B cell activation; studied molecular interactions of WU-CAM (TIGIT) in follicular Th cells; intravital microscopy measuring neutrophil chemotaxis in response to PI3-kinase delta inhibition; measurements of mouse NK cell function in response to viral ligands.

  Immunology

  Washington University in St. Louis

  Work Authorization

  US Citizen

  UK Indefinite Leave to Remain

• 1997

  Bachelor's Degree

  Majors in Biology and Biochemistry

  Biology and Biochemistry

  Gustavus Adolphus College

• Confocal Microscopy

  Protein Purification

  Flow Cytometry

  Immunofluorescence

  Tissue Culture

  Immunohistochemistry

  Immune System

  Cell Signaling

  Monoclonal Antibodies

  Mouse Models

  Molecular Immunology

  Transfection

  Surface Plasmon Resonance

  Cell Based Assays

  Fluorescence Microscopy

  Immunoprecipitation

  Protein Expression

  Molecular Cloning

  Small White Lady's Slipper Transplanted Successfully in Northwestern Minnesota

  Tom Feiro

  Dan Svedarsky

  Restoration and Management Notes

  Small White Lady's Slipper Transplanted Successfully in Northwestern Minnesota

  Marco Colonna

  Marina Cella

  Edgar Overton

  Ilaria Tassi

  Rachel Presti

  FcRL6

  a new ITIM-bearing receptor on cytolytic cells

  is broadly expressed by lymphocytes following HIV-1 infection

  Raul Torres

  Roberta Pelanda

  Marco Colonna

  P. Strauch

  Cristina Swanson

  Journal of Experimental Medicine

  Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response

  Thomas Diacovo

  J. Hayflick

  M. Turner

  E. Clayton

  T. Graf

  W. Tino

  Y. Hou

  J. Douangpanya

  Theresa Doggett

  Kamal Puri

  Blood

  Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue

  Marco Colonna

  A new Fc receptor homolog

  FREB2

  found in germinal center B cells

  Marco Colonna

  Marina Cella

  Thomas Diacovo

  Anja Fuchs

  Fabio Facchetti

  William Vermi

  Kent Boles

  European Journal of Immunology

  A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC

  R. Kelm

  M. Getz

  M. Pittelkow

  S. Liu

  A. Rand

  C. Voigtlander

  Journal of Cellular Biochemistry

  Suppression of tissue factor expression

  cofactor activity

  and metastatic potential of murine melanoma cells by the N-terminal domain of adenovirus E1A 12S protein

  Richard J. Pleass

  Gang Wu

  Anne Dell

  Stuart Haslam

  Katy A. Lloyd

  Shona C. Moore

  Inger Sandlie

  Patricia A. Blundell

  Daniel A. Mitchell

  Zhifeng Shao

  Jianfeng He

  Marco Colonna

  David Mekhaiel

  Jan Terje Andersen

  Daniel M. Czajkowsky

  Scientific Reports

  in press

  Developing the IVIG biomimetic

  Hexa-Fc

  for drug and vaccine applications

  Marion H. Brown

  Stefanie Margraf

  Elliot King

  Clive Metcalfe

  Lee I. Garner

  Fine specificity and molecular competition in SLAM family receptor signalling

  Marco Colonna

  Anja Fuchs

  Cutting Edge: FcRL4 and FcRL5 are receptors for IgA and IgG

  Marco Colonna

  Susan Gilfillan

  Fc receptor-like A associates with intracellular IgG and IgM but is dispensable for antigen-specific immune responses

  Miami University

  Washington University in St. Louis

  University of Cambridge

  University of Oxford

  Washington University in St. Louis

  University of Cambridge

  Functional studies of uncharacterized cell surface receptors

  including through generation of new monoclonal antibodies

  human leukocyte differentiation and stimulation

  and phenotypic characterization of knockout mice; screening for receptor-ligand interactions of recombinant proteins by surface plasmon resonance; analysis of human gene polymorphisms linked to autoimmune disease.

  Research Associate

  Cambridge

  United Kingdom

  Studied protein-protein interactions between SLAM-family receptors and proximal signalling proteins by surface plasmon resonance and mass spectrometry; functional studies of NK cells following shRNA targeting of signalling mediators; analysis of receptor-ligand interactions for cell surface proteins.

  University of Oxford

  Miami University

  Oxford

  OH

  USA

  Assistant Professor

  American Association of Immunologists

  Partners in Scholarship

  Gustavus Adolphus College

  Norelius Service Award

  Gustavus Adolphus College

  Marie Curie International Incoming Fellowship

  European Commission 7th Framework Programme