Resume

• 2012

  Department of Anthropology

  Laboratory for Human Biology Research

  Research Associate Professor

  Northwestern University

  Department of Physiology

  Conducted research on the effect of chronic pain on learning using classical conditioning (i.e.

  eye-blink) methods in humans.

  Research Associate Professor

  Northwestern University

  Feinberg School of Medicine

• 2004

  Department of Neurobiology and Physiology

  Dr. Horton is an ecological physiologist and endocrinologist. She conducts research on the neural and endocrine mechanisms by which environmental signals alter reproduction

  metabolism and behavior. She uses a wide range of techniques (ranging from behavioral assessments to radiotelemetry to RNA and DNA quantification) to monitor experimental outcomes.

  Research Associate Professor

  Northwestern University

• 1994

  Teresa

  Horton

  Northwestern University

  Northwestern University

  Feinberg School of Medicine

  Kent State University

  Evanston

  IL

  In the Program in Biological Sciences I taught courses in endocrinology and animal behavior to upper division undergraduate students and first and second year graduate students. I also taught introductory courses in human reproduction and general biology for non-majors and advise freshman and biology majors.

  Lecturer

  Program in Biological Sciences

  Northwestern University

  Established a research laboratory to study reproductive biology and circadian rhythms. Taught endocrinology

  human physiology

  and general biology laboratory.

  Kent State University

  Northwestern University

  Department of Neurobiology and Physiology

  Research Assistant Professor

• 1979

  Ph.D

  Biology

• 1976

  BS

  Zoology

  University of Washington

• 1975

  The Endocrine Society

  The Society for the Study of Behavioral Neuroendocrinology

  Treasurer (2010-2013)

  The Animal Behavior Society

  Spanish

  German

  Zoology

  Amigos de las Americas - Ecuador

  Washington State University

  Pullman

  WA

• Musical Offering

  Board Member

  Board President (Past)

  PTA

  Treasurer

  Dawes Elementary School

  Biology

  Evolutionary physiology

  Mentoring and supporting students

  Immunohistochemistry

  Research Design

  Research

  Molecular Biology

  University Teaching

  Radioimmunoassay

  Scientific Writing

  Biochemistry

  Neuroscience

  Teaching

  Science

  Western Blotting

  Microscopy

  Use of statistical methods in the design of experiments

  Cell Culture

  Laboratory

  Physiology

  Schneider

  J. S.

  C. Burgess

  T. H. Horton and J. E. Levine (2009). \"Effects of progesterone on male-mediated infant-directed aggression.\" Behav Brain Res 199(2): 340-344.

  Schneider

  J. S.

  C. Burgess

  T. H. Horton and J. E. Levine (2009). \"Effects of progesterone on male-mediated infant-directed aggression.\" Behav Brain Res 199(2): 340-344.

  Sleiter

  N.

  Y. Pang

  C. Park

  T. H. Horton

  J. Dong

  P. Thomas and J. E. Levine

  Endocrinology 150(8): 3833-3844.

  Progesterone's (P4) negative feedback actions in the female reproductive axis are exerted in part by suppression of hypothalamic GnRH release. Here we show that P4 can inhibit GnRH release by a mechanism independent of a nuclear P4 receptor (PR(A/B)). Injections of P4

  but not vehicle

  allopregnanolone

  or dexamethasone

  acutely suppressed LH levels in both wild-type and P4 receptor knockout ovariectomized mice; pituitary responsiveness to GnRH was retained during P4 treatment

  indicating a hypothalamic action. Superfusion of GnRH-producing GT1-7 cells with medium containing 10(-7) m P4 produced a rapid reduction in GnRH release. Incubation with P4 (10(-9) to 10(-7) M) inhibited forskolin-stimulated cAMP accumulation; cotreatment with pertussis toxin prevented this effect. Treatment of GT1-7 cell membranes with P4 caused activation of an inhibitory G protein (G(i))

  as shown by immunoprecipitation with a G(i) antibody of most of the increase in membrane-bound [(35)S]GTPgamma-S. Saturation binding analyses demonstrated the presence of a high affinity (K(d) 5.85 nM)

  limited capacity (Bmax 62.2 nM) binding site for P4. RT-PCR analysis revealed the presence of mRNAs encoding both isoforms of the membrane P4 receptors

  mPRalpha and mPRbeta. Western blotting

  immunocytochemistry

  and flow cytometry experiments similarly revealed expression of mPR proteins in the plasma membranes of GT1-7 cells. Treatment with mPRalpha siRNA attenuated specific P4 binding to GT1-7 cell membranes and reversed the P4 inhibition of cAMP accumulation. Taken together

  our results suggest that negative feedback actions of P4 include rapid PR(A/B)-independent effects on GnRH release that may in part be mediated by mPRs.

  Sleiter

  N.

  Y. Pang

  C. Park

  T. H. Horton

  J. Dong

  P. Thomas and J. E. Levine (2009). \"Progesterone receptor A (PRA) and PRB-independent effects of progesterone on gonadotropin-releasing hormone release.\" Endocrinology 150(8): 3833-3844.

  Horton

  T. H. (2005). \"Fetal origins of developmental plasticity: animal models of induced life history variation.\" Am J Hum Biol 17(1): 34-43.

  In collaboration with colleagues from the Chicago Botanic Garden

  the Forest Preserves of Cook County

  The Brushwood Center at Ryerson Woods

  and Northwestern University

  I coordinate a network of focus groups (the Nature

  Culture and Human Health (NCH2) Working Group) to develop of practices

  programs and policies around the topic of the health benefits of engaging with nature. \n\nNCH2 Statement of Purpose: \nThe mission of NCH2 is to advance our understanding of the benefits of nature to human health

  through original research

  the development of and analysis of existing evidence

  programs and policy. Intrinsic to this mission is the understanding that people of different ages

  genders

  ethnicities and social backgrounds may engage with nature in different ways; therefore

  NCH2 will strive to engage diverse peoples with nature in culturally relevant and sensitive ways. \nThis mission will be carried out by:\n\t\t1. Organizing focus groups to address specific topics. Each focus group will develop a \n set of priorities and a time line within which to address those priorities. \n\t\t2. Providing a network for sharing information developed by the focus groups. \n\t\t3. Communicating information about existing research

  programs

  and policies \n developed by coalition members at the local

  regional

  and national levels. \n\t\t4. Using the information generated by or shared through the focus groups to develop \n new practices

  programs and policy. \n

  Horton