Resume

• 2006

  Doctor of Philosophy (Ph.D.)

  Physiology

  Penn State University

• 2003

  Master of Science (M.S.)

  Physiology

  Penn State University

• 1998

  Bachelor of Science (B.S.)

  Biology

  Penn State University

• Immunohistochemistry

  Animal Models

  Western Blotting

  Confocal Microscopy

  ELISA

  Cell Culture

  SigmaPlot

  qPCR

  cell signaling

  Microsoft Office

  PCR

  Molecular Biology

  Canvas

  Protein Expression

  RNA isol

  Statistics

  Cell Based Assays

  Immunofluorescence

  Protein Purification

  Electrophoresis

  The Biarylpyrazole Compound AM251 Alters Mitochondrial Physiology Via Proteolytic Degradation of ERRα

  Isabel Gonzalez-Mariscal

  The Biarylpyrazole Compound AM251 Alters Mitochondrial Physiology Via Proteolytic Degradation of ERRα

  Ramesh Ramachandran

  Cloning and characterization of chicken fat mass and obesity associated (Fto) gene: fasting affects Fto expression

  Gonadotrophin-inhibitory hormone receptor expression in the chicken pituitary gland: potential influence of sexual maturation and ovarian steroids

  Calcitonin is expressed in the chicken pituitary gland: influence of gonadal steroids and sexual maturation

  Ramesh Ramachandran

  NAMPT (visfatin) in the chicken testis: influence of sexual maturation on cellular localization

  plasma levels and gene and protein expression

  Luigi Fontana

  David Sabatini

  Kevin Becker

  M Capri

  D Villareal

  L Jebailey

  DW Lamming

  SD Crosby

  Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile

  Adiponectin and its receptors are expressed in the chicken testis: influence of sexual maturation on testicular ADIPOR1 and ADIPOR2 mRNA abundance

  Bethany Carboneau

  Of mice and men: the benefits of caloric restriction

  exercise

  and mimetics

  Julie Mattison

  Olga Carlson

  Wook Kim

  YK Shin

  Isabel Gonzalez-Mariscal

  Josephine Egan

  Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet

  Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens

  Unique profile of chicken adiponectin

  a predominantly heavy molecular weight multimer

  and relationship to visceral adiposity

  M Sanghvi

  The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein

  Gonadotropin-inhibitory hormone (GnIH) receptor gene is expressed in the chicken ovary: potential role of GnIH in follicular maturation

  JE Pesall

  R Vasilatos-Younken

  DC McFarland

  JA Hadley

  Ramesh Ramachandran

  Nampt/visfatin/PBEF affects expression of myogenic regulatory factors and is regulated by interleukin-6 in chicken skeletal muscle cells

  Identification of calcitonin expression in the chicken ovary: influence of follicular maturation and ovarian steroids

  Y Li

  M Wei

  J Hu

  MW McBurney

  VD Longo

  SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice

  Susan

  E. Coli Reference Center

  The Pennsylvania State University

  Harford Community College

  The Pennyslvania State University

  GlaxoSmithKline

  National Institute on Aging/NIH

  Community College of Baltimore County

  Harford Community College

  Adjunct Faculty

  •\tInstructed Anatomy and Physiology I and II

  Community College of Baltimore County

  E. Coli Reference Center

  The Pennsylvania State University

  University Park

  PA

  • Investigated the role of Brachyspira spp. in dirty egg syndrome\n• Cultured and inventoried various strains of Escherichia coli

  Research Technician

  University Park

  PA

  • Defined changes in Nampt expression during growth/sexual maturity\n• Investigated the regulation of Nampt expression in satellite cells \n• Identified ovarian granulosa and thecal cells as a source of calcitonin\n• Identified calcitonin production in the endochondral growth plate\n• Investigated the role of calcitonin in tibial dyschondroplasia

  Graduate Research Assistant

  The Pennyslvania State University

  Baltimore

  MD

  •\tInvestigated the role of novel

  peripherally-specific cannabinoid receptor inverse agonists on pancreatic beta cell function as potential therapeutics for type 2 diabetes mellitus \n•\tDetermined the molecular mechanisms involved in estrogen related receptor α degradation by cannabinoid receptor inverse agonists and elucidate subsequent changes to mitochondrial physiology\n•\tPresented data at national and international meetings \n•\tAnalyzed data

  prepare manuscripts and publish in peer-reviewed journals\n•\tServed as an ad hoc reviewer for peer-reviewed journals\n•\tProvided training on laboratory equipment and procedures \n•\tPresented data at weekly data sessions and journal clubs\n•\tServed as a judge for post-baccalaureate poster competitions\n•\tMentored 2 Post-baccalaureate students and 1 summer student with their research projects and preparation of poster presentations

  Postdoctoral Fellow

  National Institute on Aging/NIH

  • Administered experimental pharmaceuticals to mice

  rats

  and rabbits\n• Performed cesarean sections to examine drug effects on reproduction

  GlaxoSmithKline