Sharif University of Technology

Research Assistant

Developed a 3D-1D multi-scale CFD model for numerical investigation of blood flow in Total CavoPulmonary Connection (TCPC); Created 3D models based on patient-specific geometries via image processing on CT-scan images; Used variable skills such as Fluent, C++/C programming, and optimization to simulate and analyze the fluid flow; Constantly communicated with interdisciplinary team members in different fields.

Texas A&M University

Postdoctoral Researcher

Developed 1D analysis models for centrifugal compressors and refrigeration systems.

Texas A&M University

Graduate Research Scientist

Conducted Design, Simulation, and CFD/CAE analysis of the Ultra-High Efficiency Gas Turbine Engine (UHEGT); completed a 2D (space-time) engine simulation code to model engine dynamic performance in variable design and off-design conditions; simulations and analysis on a high-performance computer (HPC) system; developed design and simulation algorithms in FORTRAN and MATLAB; utilized analytical techniques to optimize the gas turbine engine performance.

Supira Medical

Senior Simulation Engineer

Seyed Mostafa worked at Supira Medical as a Senior Simulation Engineer

Berkeh Pump Co.

CFD Analyst Intern

Simulated axial water pumps using computational fluid dynamics (CFD); performed data analysis and optimization studies for different pumps to improve their performance; applied analytical and simulation tool sets such as Six Sigma, CFD and FEA to solve design, performance and manufacturing problems and optimize the design for robustness, cost and quality.

SoftInWay Inc. - Turbomachinery Design, Analysis and Optimization

Turbomachinery Engineer Intern

Collaborated with a team of engineers and software developers in development and application of a design and simulation software for turbomachinery components; incorporated CFD, CAE, data analytics, and optimization subject matter expertise in the SoftInWay platform; fostered relationships with turbo industry vendor-partners; supported project management in ensuring successful deployment of the software and improved safety, reliability and profitability for customers.

Numerical Investigation of Antegrade Flow Effects on Flow Pulsations in Fontan Operation

Int. Journal of Biomedical Engineering and Technology

This study considers blood flow in Total Cavopulmonary Connection (TCPC) morphology, created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; because of right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea stating that keeping Main Pulmonary Artery (MPA) partially open, would increase pulmonary flow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations, by means of Computational Fluid Dynamics (CFD). The 3-D geometry is reconstructed from CT Angiography (CTA) scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or Pulmonary Stenosis (PS) is virtually added to the original geometry. Inlet velocity profiles are obtained from Echocardiography data of the same patient. AF profile in a cardiac cycle is obtained from a general pressure cycle of left ventricle, assuming a linear relationship between pressure gradient and flow rate in PS. Flow field is studied in six different models in which average AF increasingly changes from 0 to 14% of total cardiac flow, using FLUENT. The results show that adding AF increases Pulsatility Index (PI) in both left and right pulmonary artery (LPA and RPA respectively), with a maximum amount of 140% in LPA. Moreover, adding AF leads to an increase in energy loss of the TCPC region, with a maximum amount of 67%. The addition of AF also increases pulmonaryto- systemic flow ratio which leads to an increase in total cardiac flow rate and hence heart power.

Numerical Investigation of Antegrade Flow Effects on Flow Pulsations in Fontan Operation

Int. Journal of Biomedical Engineering and Technology

This study considers blood flow in Total Cavopulmonary Connection (TCPC) morphology, created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; because of right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea stating that keeping Main Pulmonary Artery (MPA) partially open, would increase pulmonary flow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations, by means of Computational Fluid Dynamics (CFD). The 3-D geometry is reconstructed from CT Angiography (CTA) scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or Pulmonary Stenosis (PS) is virtually added to the original geometry. Inlet velocity profiles are obtained from Echocardiography data of the same patient. AF profile in a cardiac cycle is obtained from a general pressure cycle of left ventricle, assuming a linear relationship between pressure gradient and flow rate in PS. Flow field is studied in six different models in which average AF increasingly changes from 0 to 14% of total cardiac flow, using FLUENT. The results show that adding AF increases Pulsatility Index (PI) in both left and right pulmonary artery (LPA and RPA respectively), with a maximum amount of 140% in LPA. Moreover, adding AF leads to an increase in energy loss of the TCPC region, with a maximum amount of 67%. The addition of AF also increases pulmonaryto- systemic flow ratio which leads to an increase in total cardiac flow rate and hence heart power.

Generating a Pulsatile Pulmonary Flow after Fontan Operation by Means of Computational Fluid Dynamics (CFD)

APS March Meeting, Dallas, Texas

Numerical Investigation of Antegrade Flow Effects on Flow Pulsations in Fontan Operation

Int. Journal of Biomedical Engineering and Technology

This study considers blood flow in Total Cavopulmonary Connection (TCPC) morphology, created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; because of right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea stating that keeping Main Pulmonary Artery (MPA) partially open, would increase pulmonary flow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations, by means of Computational Fluid Dynamics (CFD). The 3-D geometry is reconstructed from CT Angiography (CTA) scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or Pulmonary Stenosis (PS) is virtually added to the original geometry. Inlet velocity profiles are obtained from Echocardiography data of the same patient. AF profile in a cardiac cycle is obtained from a general pressure cycle of left ventricle, assuming a linear relationship between pressure gradient and flow rate in PS. Flow field is studied in six different models in which average AF increasingly changes from 0 to 14% of total cardiac flow, using FLUENT. The results show that adding AF increases Pulsatility Index (PI) in both left and right pulmonary artery (LPA and RPA respectively), with a maximum amount of 140% in LPA. Moreover, adding AF leads to an increase in energy loss of the TCPC region, with a maximum amount of 67%. The addition of AF also increases pulmonaryto- systemic flow ratio which leads to an increase in total cardiac flow rate and hence heart power.

Generating a Pulsatile Pulmonary Flow after Fontan Operation by Means of Computational Fluid Dynamics (CFD)

APS March Meeting, Dallas, Texas

3D-1D Simulation of Flow in Fontan Operation: Effects of Antegrade Flow on Flow Pulsations

Scientia Iranica Journal

Fontan surgical procedure in patients with a single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; since the right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea of increasing pulmonary flow pulsations by keeping main pulmonary artery (MPA) partially open while it was closed in ordinary TCPC operation. The purpose of the present study is to verify the effects of antegrade flow (AF) coming through stenosed MPA on pulmonary flow pulsations. The 3-D geometry is reconstructed from CT angiography scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or pulmonary stenosis (PS) is virtually added to the original geometry. We applied a 3D-1D coupled method to simulate blood flow in this situation more precisely. The results show that adding AF increases pulsatility index (PI) in both left and right pulmonary artery (LPA and RPA respectively). Moreover, adding AF leads to an increase in energy loss. It also increases the pulmonary-to-systemic flow ratio leading to increase in total cardiac flow rate and hence heart power.

Numerical Investigation of Antegrade Flow Effects on Flow Pulsations in Fontan Operation

Int. Journal of Biomedical Engineering and Technology

This study considers blood flow in Total Cavopulmonary Connection (TCPC) morphology, created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; because of right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea stating that keeping Main Pulmonary Artery (MPA) partially open, would increase pulmonary flow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations, by means of Computational Fluid Dynamics (CFD). The 3-D geometry is reconstructed from CT Angiography (CTA) scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or Pulmonary Stenosis (PS) is virtually added to the original geometry. Inlet velocity profiles are obtained from Echocardiography data of the same patient. AF profile in a cardiac cycle is obtained from a general pressure cycle of left ventricle, assuming a linear relationship between pressure gradient and flow rate in PS. Flow field is studied in six different models in which average AF increasingly changes from 0 to 14% of total cardiac flow, using FLUENT. The results show that adding AF increases Pulsatility Index (PI) in both left and right pulmonary artery (LPA and RPA respectively), with a maximum amount of 140% in LPA. Moreover, adding AF leads to an increase in energy loss of the TCPC region, with a maximum amount of 67%. The addition of AF also increases pulmonaryto- systemic flow ratio which leads to an increase in total cardiac flow rate and hence heart power.

Generating a Pulsatile Pulmonary Flow after Fontan Operation by Means of Computational Fluid Dynamics (CFD)

APS March Meeting, Dallas, Texas

3D-1D Simulation of Flow in Fontan Operation: Effects of Antegrade Flow on Flow Pulsations

Scientia Iranica Journal

Fontan surgical procedure in patients with a single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; since the right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea of increasing pulmonary flow pulsations by keeping main pulmonary artery (MPA) partially open while it was closed in ordinary TCPC operation. The purpose of the present study is to verify the effects of antegrade flow (AF) coming through stenosed MPA on pulmonary flow pulsations. The 3-D geometry is reconstructed from CT angiography scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or pulmonary stenosis (PS) is virtually added to the original geometry. We applied a 3D-1D coupled method to simulate blood flow in this situation more precisely. The results show that adding AF increases pulsatility index (PI) in both left and right pulmonary artery (LPA and RPA respectively). Moreover, adding AF leads to an increase in energy loss. It also increases the pulmonary-to-systemic flow ratio leading to increase in total cardiac flow rate and hence heart power.

The Ultrahigh Efficiency Gas Turbine Engine with Stator Internal Combustion

Journal of Engineering for Gas Turbines and Power

The current article introduces a physics-based revolutionary technology that enables energy efficiency and environmental compatibility goals of future generation aircraft and power generation gas turbines (GTs). An ultrahigh efficiency GT technology (UHEGT) is developed, where the combustion process is no longer contained in isolation between the compressor and turbine, rather distributed in three stages and integrated within the first three high pressure (HP) turbine stator rows. The proposed distributed combustion results in high thermal efficiencies, which cannot be achieved by conventional GT engines. Particular fundamental issues of aerothermodynamic design, combustion, and heat transfer are addressed in this study along with comprehensive computational fluid dynamics (CFD) simulations. The aerothermodynamic study shows that the UHEGT-concept improves the thermal efficiency of GTs 5–7% above the current most advanced high efficiency GT engines, such as Alstom GT24. Multiple configurations are designed and simulated numerically to achieve the optimum configuration for UHEGT. CFD simulations include combustion process in conjunction with a rotating turbine row. Temperature and velocity distributions are investigated as well as power generation, pressure losses, and NOx emissions. Results show that the configuration in which fuel is injected into the domain through cylindrical tubes provides the best combustion process and the most uniform temperature distribution at the rotor inlet.

Numerical Investigation of Antegrade Flow Effects on Flow Pulsations in Fontan Operation

Int. Journal of Biomedical Engineering and Technology

This study considers blood flow in Total Cavopulmonary Connection (TCPC) morphology, created in Fontan surgical procedure in patients with single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; because of right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea stating that keeping Main Pulmonary Artery (MPA) partially open, would increase pulmonary flow pulsations. MPA gets closed in ordinary TCPC operation. The purpose of current study is to verify effects of Antegrade Flow (AF) coming through stenosed MPA on pulmonary flow pulsations, by means of Computational Fluid Dynamics (CFD). The 3-D geometry is reconstructed from CT Angiography (CTA) scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or Pulmonary Stenosis (PS) is virtually added to the original geometry. Inlet velocity profiles are obtained from Echocardiography data of the same patient. AF profile in a cardiac cycle is obtained from a general pressure cycle of left ventricle, assuming a linear relationship between pressure gradient and flow rate in PS. Flow field is studied in six different models in which average AF increasingly changes from 0 to 14% of total cardiac flow, using FLUENT. The results show that adding AF increases Pulsatility Index (PI) in both left and right pulmonary artery (LPA and RPA respectively), with a maximum amount of 140% in LPA. Moreover, adding AF leads to an increase in energy loss of the TCPC region, with a maximum amount of 67%. The addition of AF also increases pulmonaryto- systemic flow ratio which leads to an increase in total cardiac flow rate and hence heart power.

Generating a Pulsatile Pulmonary Flow after Fontan Operation by Means of Computational Fluid Dynamics (CFD)

APS March Meeting, Dallas, Texas

3D-1D Simulation of Flow in Fontan Operation: Effects of Antegrade Flow on Flow Pulsations

Scientia Iranica Journal

Fontan surgical procedure in patients with a single ventricle heart disease. Ordinary process of TCPC operation reduces pulmonary blood flow pulsatility; since the right ventricle being bypassed. This reduction may limit the long term outcome of Fontan circulation. There is an idea of increasing pulmonary flow pulsations by keeping main pulmonary artery (MPA) partially open while it was closed in ordinary TCPC operation. The purpose of the present study is to verify the effects of antegrade flow (AF) coming through stenosed MPA on pulmonary flow pulsations. The 3-D geometry is reconstructed from CT angiography scan of a patient who has undergone an ordinary TCPC procedure. The stenosed MPA or pulmonary stenosis (PS) is virtually added to the original geometry. We applied a 3D-1D coupled method to simulate blood flow in this situation more precisely. The results show that adding AF increases pulsatility index (PI) in both left and right pulmonary artery (LPA and RPA respectively). Moreover, adding AF leads to an increase in energy loss. It also increases the pulmonary-to-systemic flow ratio leading to increase in total cardiac flow rate and hence heart power.

The Ultrahigh Efficiency Gas Turbine Engine with Stator Internal Combustion

Journal of Engineering for Gas Turbines and Power

The current article introduces a physics-based revolutionary technology that enables energy efficiency and environmental compatibility goals of future generation aircraft and power generation gas turbines (GTs). An ultrahigh efficiency GT technology (UHEGT) is developed, where the combustion process is no longer contained in isolation between the compressor and turbine, rather distributed in three stages and integrated within the first three high pressure (HP) turbine stator rows. The proposed distributed combustion results in high thermal efficiencies, which cannot be achieved by conventional GT engines. Particular fundamental issues of aerothermodynamic design, combustion, and heat transfer are addressed in this study along with comprehensive computational fluid dynamics (CFD) simulations. The aerothermodynamic study shows that the UHEGT-concept improves the thermal efficiency of GTs 5–7% above the current most advanced high efficiency GT engines, such as Alstom GT24. Multiple configurations are designed and simulated numerically to achieve the optimum configuration for UHEGT. CFD simulations include combustion process in conjunction with a rotating turbine row. Temperature and velocity distributions are investigated as well as power generation, pressure losses, and NOx emissions. Results show that the configuration in which fuel is injected into the domain through cylindrical tubes provides the best combustion process and the most uniform temperature distribution at the rotor inlet.

Numerical Simulation of the Multistage Ultra-High Efficiency Gas Turbine Engine, UHEGT

ASME Turbo Expo (IGTI), Charlotte, NC, USA

The Ultra-High Efficiency Gas Turbine Engine (UHEGT) was introduced in our previous studies [1]-[3]. In UHEGT, the combustion process is no longer contained in isolation between the compressor and turbine, rather distributed in multiple stages and integrated within the high-pressure turbine stator rows. Compared to the current most advanced conventional gas turbines, UHEGT considerably improves the efficiency and output power of the engine while reducing its emissions and size. In the present study, a complete six-stage turbine with three stator internal combustors is designed for UHEGT. The turbine is designed for a single spool turboshaft system used for power generation. A thermodynamic cycle that has a base thermal efficiency of above 45% is designed based on an ideal mixture of methane and air. Preliminary flow path for each turbine stage is designed by 1D/2D approach (meanline calculation). The combustors, designed based on our previous [1] and parallel studies, consist of cylindrical tubes extended from hub to shroud with thin slots on top and bottom for gaseous fuel injection. CFD calculation (via ANSYS CFX) is used to simulate the high pressure turbine stages (stage 1 to 3). The simulations are unsteady, they are performed for ten total components and include a multi-species combustion process along with the rotor motion. The flow path is modified based on the CFD results in order to reduce separation and losses while enabling maximum mixing of fuel and air and reducing temperature non-uniformities. Flow patterns, secondary flow losses, temperature distribution, and pollutant emissions are presented and analyzed in the results. The results show that a relatively uniform temperature distribution is achieved at the inlet of each rotor and the system performs very well regarding the output power and flow patterns.