Resume

• 2015

  Doctor of Philosophy (Ph.D.)

  Bioinformatics

  University of Louisville

• 2012

  Spanish

  English

  Master's Degree

  Mathematics

  University of Louisville

  Manogue

  Master's Degree

  Biostatistics

  University of Louisville

• 2008

  Bachelor of Science (B.S.)

  Mathematics

  Seattle University

• Backside Learning Center

  English as a second language instructor

  Family Education Program tutor

  FEP summer camp leader

  Board Member; Warehouse Volunteer; Food Rescue Program Volunteer

  3/2020-Current: Volunteer in the warehouse and in the Food Rescue Program\n6/2020-Current: Member

  Board of Directors

  CASA DE PEREGRINOS FOOD PANTRY

  Volunteer Classroom Assistant

  King County Juvenile Detention Center

  Statistical Genetics

  R (Programming Language)

  Unix

  Statistical Consulting

  Bioinformatics

  Biostatistics

  SAS

  Linux

  Object Oriented Design

  Statistical Modeling

  Machine Learning

  Statistical Programming

  Bayesian Statistics

  Proteomics

  Data Mining

  SQL

  Research

  Metabolomics

  Python

  Statistics

  Exercise-induced changes in glucose metabolism promote physiologic cardiac growth

  Daniel Conklin

  Kartik Katragadda

  Detlef Obal

  Lindsey McNally

  Shizuka Uchida

  Paul Epstein

  Steven Jones

  Aruni Bhatnagar

  Bradford Hill

  Andrew Gibb

  Exercise-induced changes in glucose metabolism promote physiologic cardiac growth

  Andrew DeFilippis

  Shesh Rai

  Ayesha Singh

  Joseph B Moore IV

  Imtiaz Ismail

  Vallari Kothari

  Diana Otero

  David Day Song

  Alok Amraotkar

  Platelet Count and Mean Platelet Volume at the Time of and After Acute Myocardial Infarction

  Andrew DeFilippis

  Aruni Bhatnagar

  Shesh Rai

  Eric Rouchka

  Bradford G. Hill

  Systems characterization of differential plasma metabolome perturbations following thrombotic and non-thrombotic myocardial infarction

  Brian S Shumway

  Alfred Bennett Jenson

  Shesh Rai

  Joongho Joh

  Shin-je Ghim

  Maryam Zahin

  Sujita Khanal

  Histologic Variation in High Grade Oral Epithelial Dysplasia When Associated With High-Risk Human Papillomavirus

  When Given a Lemon

  Make Lemonade: Revising Cardiovascular Risk Prediction Scores

  Goetz Kloecker

  Farhad Khosravi

  Shesh Rai

  Classification of biosensor time series using dynamic time warping: applications in screening cancer cells with characteristic biomarkers

  BayesianGLasso: An R package for estimating Gaussian Graphical Models via a block Gibbs sampler for the Bayesian Graphical Lasso

  Shesh Rai

  Andrew DeFilippis

  Evaluation of classifier performance for multiclass phenotype discrimination in untargeted metabolomics

  Inferring metabolite interactomes via molecular structure informed Bayesian graphical model selection with an application to coronary artery disease

  Aruni Bhatnagar

  Eric Rouchka

  Glenn Hirsch

  Shesh Rai

  Alok Amraotkar

  Bradford Hill

  Andrew DeFilippis

  Identification of a plasma metabolomic signature of thrombotic myocardial infarction that is distinct from non-thrombotic myocardial infarction and stable coronary artery disease

  Andrew Defilippis

  Aruni Bhatnagar

  Shesh Rai

  Affan B Irfan

  Charles Hargis

  Shahab Ghafghazi

  Alok Amraotkar

  Presence of multiple coronary angiographic characteristics for the diagnosis of acute coronary thrombus

  Aruni Bhatnagar

  Sotirios Tsimikas

  Gregor Leibundgut

  Frederick K Korley

  Charles W Hargis

  Imtiaz Ismail

  Shalin Kothari

  Alok Amraotkar

  Ilya Chernyavskiy

  Andrew Paul Defilippis

  Circulating levels of plasminogen and oxidized phospholipids bound to plasminogen distinguish between atherothrombotic and non-atherothrombotic myocardial infarction

  David Hein

  Xiang Zhang

  Christopher States

  Marcus Stepp

  Mark Doll

  Xinmin Yin

  Untargeted polar metabolomics of transformed MDA-MB-231 breast cancer cells expressing varying levels of human arylamine N-acetyltransferase 1

  Balaji Panchapakesan

  Shesh Rai

  Eric Wickstrom

  Goetz Kloecker

  Christopher Lambert

  Farhad Khosravi

  Static micro-array isolation

  dynamic time series classification

  capture and enumeration of spiked breast cancer cells in blood: The nanotube-CTC chip

  David W Hein

  Carolyn Klinge

  Marcus Stepp

  Mark Doll

  Knockout of Human Arylamine N‐Acetyltransferase 1 (NAT1) in MDA‐MB‐231 Breast Cancer Cells Leads to Increased Reserve Capacity

  Maximum Mitochondrial Capacity

  and Glycolytic Reserve Capacity

  Balaji Panchapakesan

  Eric Wickstrom

  Goetz Kloecker

  Shesh Rai

  Farhad Khosravi

  Label-free capture of breast cancer cells spiked in buffy coats using carbon nanotube antibody micro-arrays

  Brian S Shumway

  Shesh Rai

  Alfred Bennett Jenson

  Shin-je Ghim

  Joongho Joh

  Eric T. Cole

  Sujita Khanal

  Human Papillomavirus Detection In Histological Samples of Multifocal Epithelial Hyperplasia: A Novel Demographic Presentation

  John Wenz

  Tamre Cardoso

  J. McLean Sloughter

  Hugh Safford

  Dave Fournier

  Joel M Egan

  Assessment of a Jeffrey Pine Beetle Outbreak from 1991-1996 near Spooner Junction

  Lake Tahoe Basin

  Wisdom of artificial crowds feature selection in untargeted metabolomics: An application to the development of a blood-based diagnostic test for thrombotic myocardial infarction

  Andrew P DeFilippis

  Roman V Yampolskiy

  Wisdom of artificial crowds feature selection in untargeted metabolomics: An application to the development of a blood-based diagnostic test for thrombotic myocardial infarction

  Dave Fournier

  Hugh Safford

  Ke Wu

  Tamre Cardoso

  J. McLean Sloughter

  Joel M. Egan

  Multi-temporal ecological analysis of Jeffrey pine beetle outbreak dynamics within the Lake Tahoe Basin

  Patrick

  United States Marine Corps

  Humana

  DiscernDx

  New Mexico State University

  Theravance

  Seattle University

  University of Louisville

  University of Louisville

  Biometrics Intern

  San Francisco Bay Area

  Theravance

  Louisville

  Kentucky

  •\tDeveloped novel computational methods for metabolomics

  proteomics

  and transcriptomics \n•\tServed as the lead bioinformatics scientist in developing a multi-omic (metabolomics & proteomics) method for differentiating myocardial infarction (heart attack) subtypes\n•\tDeveloped machine learning methodology to facilitate the detection of circulating cancer cells using carbon nanotube micro-arrays\n•\tProvided bioinformatics and biostatistical support to scientists and clinicians at the Institute of Molecular Cardiology & at the JG Brown Cancer Center

  Graduate Research Assistant

  University of Louisville

  Louisville

  Kentucky

  • I developed predictive models for forecasting plan-level performance across multiple clinical quality measures\n• I developed an integrated model for forecasting clinical quality performance subject to a new set of state \"pay-for-performance\" guidelines for Medicaid plans\n• Executed many ad-hoc statistical analyses for internal teams within clinical quality

  Clinical Analytics Consultant

  Humana

  Las Cruces

  New Mexico Area

  Assistant Professor of Applied Statistics

  New Mexico State University

  Fort Knox

  Kentucky

  Sergeant

  United States Marine Corps

  University of Louisville

  DiscernDx

  Palo Alto

  California

  • Development of machine learning applications for the analysis of high-dimensional mass spectrometry data generated from clinical samples to support DiscernDx's diagnostic objectives\n• Statistical analyses to support chromatography and mass spectrometry method development and optimization\n• Development of cloud computing architectures and strategies for processing and analyzing high-dimensional mass spectrometry data\n• Other bioinformatic projects in support of scientific teams

  Bioinformatics Data Scientist

  Louisville

  Kentucky

  Courses taught: Introductory Statistics

  Contemporary Mathematics

  College Algebra

  and Essentials of Calculus.

  Graduate Teaching Assistant

  University of Louisville

  Seattle

  Developed spatial statistical models for predicting mortality in pine trees throughout different phases of bark beetle epidemics.

  Research Assistant

  Seattle University