Resume

• 2010

  Master’s Degree

  Clinical and Population Translational Sciences

  Investigation of SNPs within the corticosteroid pathway and association with lung function

  steroid use and healthcare utilization in individuals with asthma.

  Wake Forest University

• 2001

  PhD

  Molecular Genetics/Neurobiology and Anatomy

  In my project I was undertaking a biotherapeutic approach in efforts to mitigate developmental and stress induced cell death in motoneurons. I cloned the Hsc70 sequence and developed methods to generated the full length protein and protein fragments and mutants for use in vitro and in vivo. I was also involved in its use in a mouse model of amyotrophic lateral sclerosis (ALS). Later

  I was responsible for a project to search for novel biomarkers in ALS.

  Wake Forest University School of Medicine

• 1994

  BS

  Biology

• Cell Culture

  Animal Models

  Molecular Biology

  Western Blotting

  Immunohistochemistry

  Robinson

  Wake Forest School of Medicine

  UNC Lineberger Comprehensive Cancer Center

  Wake Forest University

  Wake Forest Baptist Health

  Guilford Technical Community College

  Elucidation of disease specific biomarkers in ALS\nInvestigation of the motoneuron response to stress.\n\nMechanisms of the motoneuron stress response

  Wake Forest University

  Clinical Protocol and Grant Writer

  Wake Forest Baptist Health

  Wake Forest University

  Center for Genomics

  We are working to determine the mechanisms associated with the multimerization status of adiponectin in relation to the genotype of individuals with diabetes.

  Research Fellow

  Wake Forest School of Medicine

  Clinical Protocol Development Associate

  UNC Lineberger Comprehensive Cancer Center

  Adjunct Instructor

  Teach Anatomy and Physiology Lecture and Laboratories.

  Guilford Technical Community College

  Wake Forest University

  Wake Forest University/Center for Genomics and Personalized Medicine Research

  My projects include a number of different approaches to examine the pathological influences of the IL6 inflammatory pathway in asthma. Additionally

  one my interests is the contribution of molecular chaperones to disease. In particular

  we are examining how chaperones affect the corticosteroid pathway. \n1) We determine the functional implications of IL6 and IL6 transsignaling in airway smooth muscle and how it may play a role in the pathophysiology of asthma and other obstructive pulmonary diseases. \n\n2) Also

  we investigate alterations in soluble IL6 receptor in various population of individuals with asthma and chronic obstuctive pulmonary disease. \n\n3) Finally

  we are also investigating genetic mutations within the steroid pathway to determine potential association with lung function

  steroid use and healthcare utilization.

  Research Fellow/K12 Scholar

  Winston Salem

  NC

  Principal Investigator/Study Director: \nTest products for the treatment of cutaneous radiation injury. Provide project management

  data management

  interim statistical analyses

  and study reporting responsibilities.\n\nCo-Investigator:\nDevelop and test recombinant protein biotherapeutics and derivatives for use and treatment in a model of amyotrophic lateral sclerosis (Lou Gehrig's Disease). Characterize the molecular and physiological targets of the biotherapeutic.\n\nExamine inflammatory pathways contributing to ALS pathology.\n\nInvestigate gene expression in skeletal muscle to uncover expression markers associated with various parameters of ALS pathology.\n\nTeach graduate level Cell Death Lectures.

  Instructor

  Wake Forest University