Kim O'Neill
- Courses2
- Reviews35
- School: Brigham Young University
- Campus:
- Department: Biology
- Email address: Join to see
- Phone: Join to see
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Location:
Provo, UT - 84602 - Dates at Brigham Young University: July 2015 - January 2020
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N/A
Would take again: Yes
For Credit: Yes
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Awesome
Prof. Kim is very funny and I really enjoyed his class! You can see that he cares about his students and their success. In his grading criteria, an 85% is equivalent to an A which I find really nice. However, I feel like I wasted $135 on the textbook. I would suggest you do the one week trial to get all of the online assignments done in one go. He gives interesting lectures as well!
Biography
Brigham Young University - Biology
Resume
1980
Brigham Young University
Professor
Doctor of Philosophy (Ph.D.)
Biomedical Sciences
University of Ulster
Microscopy
Biotechnology
Cell Biology
Leadership
ELISA
Biochemistry
Statistics
Microsoft Excel
Molecular Biology
University Teaching
Higher Education
PCR
Genetics
Flow Cytometry
Lifesciences
Western Blotting
Public Speaking
Research
Cell Culture
Science
Anticancer Activities of Selected Species of North American Lichen Extracts
Larry St. Clair
Cancer is the second leading cause of human deaths in the USA. Despite continuous efforts to treat cancer over the past 50 years
human mortality rates have not decreased significantly. Natural products
such as lichens
have been good sources of anticancer drugs. This study reports the cytotoxic activity of crude extracts of 17 lichen species against Burkitt’s lymphoma (Raji) cells. Out of the 17 lichen species
extracts from 14 species showed cytotoxicity against Raji cells. On the basis of IC50 values
we selected Xanthoparmelia chlorochroa and Tuckermannopsis ciliaris to study the mechanism of cell death. Viability of normal lymphocytes was not affected by the extracts of X. chlorochroa and T. ciliaris. We found that extracts from both lichens decreased proliferation
accumulated cells at the G0/G1 stage
and caused apoptosis in a dosedependent\nmanner. Both lichen extracts also caused upregulation of p53. The T. ciliaris extract upregulated the expression ofTK1 but X. chlorochroa did not.We also found that usnic
salazinic
constictic
and norstictic acids were present in the extract of X. chlorochroa
whereas protolichesterinic acid in T. ciliaris extracts. Our data demonstrate that lichen extracts merit further research as a potential source of anticancer drugs.
Anticancer Activities of Selected Species of North American Lichen Extracts
Richard Robison
Chris Hamilton
A book chapter describing the process of oxidative stress and its role in prostate cancer and other diseases of the prostate.
Oxidative Stress Imbalance in the Development of Prostate Cancer
BK Murray
KO Monson
JG Robison
Decreased DNA repair rates and protection from heat induced apoptosis mediated by electromagnetic field exposure
O'Neill
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