Resume

• 2014

  St. John's University

  New York University

  Queens

  NY

  Courses: CHE 2230/2240 (Organic Chemistry I and II for Biology Majors)

  CHE 1120/1130 (Intro to General & Organic Chemistry for Pharm.D. and Physician's Assistant Majors)

  CHE 3260 (Advanced Organic Chemistry III for Chemistry and Biology Majors).\n\nResponsibilities: CHE 1120 and 1130 Course Coordinator

  CHE 1122R Recitation Coordinator.

  Visiting Assistant Professor of Chemistry

  St. John's University

  Tandon School of Engineering

  Courses: CM-UY 1004 (General Chemistry for Engineers)

  CM-UY 2213/2223 (Organic Chemistry I and Organic Chemistry II)

  CM-UY 3514 (Analytical Chemistry)

  CM-UY 2102 (Molecular Modeling in Chemistry)\n\nResponsibilities: General Chemistry Manager (Coordinating Adjunct Instructors and TAs)

  Industry Assistant Professor

  New York University

  Thesis title: Pericyclc Reactions in Organic Synthesis\n\nDirected 2 international visiting scientists from Daiichi-Sankyo Co. in the development of an efficient new synthetic process leading to a primary author publication in a top peer-reviewed journal.\n\nCollaborated with chemical engineers on environmentally-benign methods for pharmaceutical synthesis.\n\nCo-author of 3 peer-reviewed publications in international journals; presented research in 3 public lectures.

  Massachusetts Institute of Technology

  NYU Tandon School of Engineering

  Brooklyn

  NY

  Industry Associate Professor

  Designed lecture handouts

  problem sets

  and exams for a graduate level organic synthesis class.\n\nConducted recitations for undergraduate organic chemistry classes; tutored individual students.

  Massachusetts Institute of Technology

  New York University

  Brooklyn

  NY

  Industry Associate Professor

• 2011

  Bard HS Early College Queens

  NYU Tandon School of Engineering

  Long Island City

  NY

  Courses: \n* General Chemistry with Lab\n* Organic Chemistry I and II with Lab\n* Advanced Organic Chemistry Tutorial\n\nLeadership:\n* UFT Co-Chapter Leader\n* Science Department Representative to the School Leadership Team and Executive Committee\n* College Transfer Advisor \n* New Teacher Mentor

  Assistant Professor of Chemistry

  Bard HS Early College Queens

• 2006

  Ph.D.

  Organic Chemistry

  Graduate Women at MIT

  Chemistry Outreach Program

  Massachusetts Institute of Technology

• 2002

  BA

  Chemistry

  Phi Beta Kappa

• 4

  A [4+4] annulation strategy for the synthesis of eight-membered carbocycles is reported that proceeds via a cascade involving two pericyclic processes. In the first step

  the [4+2] cycloaddition of a conjugated enyne with an electron-deficient cyclobutene generates a strained six-membered cyclic allene that isomerizes to the corresponding 1

  3-cyclohexadiene. In the second step

  this bicyclo[4.2.0]octa-2

  4-diene intermediate undergoes thermal or acid-promoted 6-electron electrocyclic ring opening to furnish a 2

  6-cyclooctatrienone. The latter transformation represents the first example of the promotion of 6-electron electrocyclic ring opening reactions by acid.

  A [4 + 4] Annulation Strategy for the Synthesis of Eight-membered Carbocycles Based on Intramolecular Cycloadditions of Conjugated Enynes

  Takafumi Kitawaki

  Katsu Okano

  Takeo Sakai

  A formal

  metal-free

  [2 + 2 + 2] cycloaddition strategy is described based on a cascade of two pericyclic processes. The first step involves an intramolecular propargylic ene reaction of a 1

  6-diyne to generate a vinylallene

  which then reacts in an inter- or intramolecular Diels−Alder reaction with an alkenyl or alkynyl dienophile. Reactions involving unsymmetrical alkenyl and alkynyl dienophiles proceed with good to excellent regioselectivity

  and the diastereoselectivity in the Diels−Alder step is also high

  with endo cycloadducts produced as the exclusive products of the reaction. In the case of alkynyl dienophiles

  [4 + 2] cycloaddition initially generates an isotoluene-type intermediate that isomerizes to the isolated aromatic product upon exposure to a catalytic amount of DBU at room temperature. The mechanism of several earlier fully intramolecular related transformations have been shown to involve an analogous process rather than the diradical-mediated pathways proposed previously.

  Formal [2 + 2 + 2] Cycloaddition Strategy Based on an Intramolecular Propargylic Ene Reaction/Diels-Alder Cycloaddition Cascade

  Jefferson Tester

  Rocco Ciccolini

  Xiao Yin Mak

  Supercritical carbon dioxide can be employed as an environmentally friendly alternative to conventional organic solvents for the synthesis of a variety of carboxylic amides. The addition of amines to ketenes generated in situ via the retro-ene reaction of alkynyl ethers provides amides in good yield

  in many cases with ethylene or isobutylene as the only byproducts of the reaction. Reactions with ethoxy alkynes are performed at 120−130 °C

  whereas tert-butoxy derivatives undergo the retro-ene reaction at 90 °C. With the exception of primary

  unbranched amines

  potential side reactions involving addition of the amines to carbon dioxide are not competitive with the desired C−N bond-forming reaction. The amide synthesis is applicable to the preparation of β-hydroxy and β-amino amide derivatives

  as well as amides bearing isolated carbon−carbon double bonds. Preliminary experiments aimed at developing an intramolecular variant of this process to afford macrolactams suggest that the application of CO2/co-solvent mixtures may offer advantages for the synthesis of large-ring compounds.

  Synthesis of Amides and Lactams in Supercritical Carbon Dioxide

  Julia

  Robinson-Surry

  Massachusetts Institute of Technology

• Organic Synthesis

  GC-MS

  ChemDraw

  IR

  Science

  Chemistry

  Laboratory

  Spectroscopy

  Research

  Organic Chemistry

  Synthetic Organic Chemistry

  Teaching

  NMR

  A [4 + 4] Annulation Strategy for the Synthesis of Eight-membered Carbocycles Based on Intramolecular Cycloadditions of Conjugated Enynes

  Jennie Fong

  Sami F. Tlais