Gloria Regisford
- Courses2
- Reviews4
- School: Prairie View A&M University
- Campus:
- Department: Biology
- Email address: Join to see
- Phone: Join to see
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Location:
100 University Dr
Prairie View, TX - 77446 - Dates at Prairie View A&M University: November 2016 - January 2020
- Office Hours: Join to see
N/A
Would take again: Yes
For Credit: Yes
0
0
Mandatory
Awesome
I was able to get an A when I took Prof. Regisford's class during the fall. The tests are usually a hundred questions, but as long as you read the material and pay attention to lectures, you will be fine.
N/A
Would take again: Yes
For Credit: Yes
0
0
Mandatory
Awesome
Prof. Regisford is very engaging. Class is lecture heavy but she makes sure that everyone understands the material. She wouldn't mind repeating information until one completely understands the topic being discussed. She also takes the time to get to know her students and she appreciates hard workers a lot!
Biography
Prairie View A&M University - Biology
Professor at Prairie View A&M University
Higher Education
Gloria
Regisford
Houston, Texas Area
Undergraduate Research Advisor and Mentor
Teach General Biology, Cell Biology and Genomics
Experience
Prairie View A&M University
Professor
Gloria worked at Prairie View A&M University as a Professor
Education
Rutgers University-New Brunswick
Doctor of Philosophy (PhD)
Reproductive Biology
Publications
Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
G3 (Bethesda, Md.)
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. We find that F elements have greater transposon density (25-50%) than euchromatic reference regions (3-11%). Among the F elements, D. grimshawi has the lowest transposon density (particularly DINE-1: 2% vs. 11-27%). F element genes have larger coding spans, more coding exons, larger introns, and lower codon bias. Comparison of the Effective Number of Codons with the Codon Adaptation Index shows that, in contrast to the other species, codon bias in D. grimshawi F element genes can be attributed primarily to selection instead of mutational biases, suggesting that density and types of transposons affect the degree of local heterochromatin formation. F element genes have lower estimated DNA melting temperatures than D element genes, potentially facilitating transcription through heterochromatin. Most F element genes (~90%) have remained on that element, but the F element has smaller syntenic blocks than genome averages (3.4-3.6 vs. 8.4-8.8 genes per block), indicating greater rates of inversion despite lower rates of recombination. Overall, the F element has maintained characteristics that are distinct from other autosomes in the Drosophila lineage, illuminating the constraints imposed by a heterochromatic milieu.
Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
G3 (Bethesda, Md.)
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. We find that F elements have greater transposon density (25-50%) than euchromatic reference regions (3-11%). Among the F elements, D. grimshawi has the lowest transposon density (particularly DINE-1: 2% vs. 11-27%). F element genes have larger coding spans, more coding exons, larger introns, and lower codon bias. Comparison of the Effective Number of Codons with the Codon Adaptation Index shows that, in contrast to the other species, codon bias in D. grimshawi F element genes can be attributed primarily to selection instead of mutational biases, suggesting that density and types of transposons affect the degree of local heterochromatin formation. F element genes have lower estimated DNA melting temperatures than D element genes, potentially facilitating transcription through heterochromatin. Most F element genes (~90%) have remained on that element, but the F element has smaller syntenic blocks than genome averages (3.4-3.6 vs. 8.4-8.8 genes per block), indicating greater rates of inversion despite lower rates of recombination. Overall, the F element has maintained characteristics that are distinct from other autosomes in the Drosophila lineage, illuminating the constraints imposed by a heterochromatic milieu.
Hydroxyapatite grafted carbon nanotubes and graphene nanosheets: promising bone implant materials.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In the present study, hydroxyapatite (HA) was successfully grafted to carboxylated carbon nanotubes (CNTs) and graphene nanosheets. The HA grafted CNTs and HA-graphene nanosheets were characterized using FT-IR, TGA, SEM and X-ray diffraction. The HA grafted CNTs and graphene nanosheets (CNTs-HA and Gr-HA) were further used to examine the proliferation and differentiation rate of temperature-sensitive human fetal osteoblastic cell line (hFOB 1.19). Total protein assays and western blot analysis of osteocalcin expression were used as indicators of cell proliferation and differentiation. Results indicated that hFOB 1.19 cells proliferate and differentiate well in treatment media containing CNTs-HA and graphene-HA. Both CNTs-HA and graphene-HA could be promising nanomaterials for use as scaffolds in bone tissue engineering.
