Erin Giles

 Erin Giles

Erin Giles

  • Courses2
  • Reviews3
May 2, 2018
N/A
Textbook used: No
Would take again: Yes
For Credit: Yes

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Mandatory



Difficulty
Clarity
Helpfulness

Awesome

Workload was kind of heavy in Dr. Giles' class, but she was totally awesome! She also allows us to pick our own topic to research. She gives very few lectures. Her class mostly involves writing a research paper and listening to presentations. She's a fair grader as well. She's also available outside of class. I honestly think she was great.

Biography

Texas A&M University College Station - Nutrition Foods

Assistant Professor at Texas A&M University
Research
Erin
Giles
College Station, Texas
My lab uses an integrative, translational approach to understand the mechanisms by which obesity promotes postmenopausal breast cancers. We’re interested in understanding how the obese microenvironment, when combined with the metabolic and hormonal changes associated with menopause, promote tumor development, survival, and growth. In parallel, we also study the role of adipose tissue inflammation in the development of metabolic disease after menopause. We hope that the knowledge gained from studying the ‘normal’ adipose and breast environments during menopause will also help us understand the changes that occur to create a tumor-promoting environment in the breast of obese women during this same window of time.


Experience

  • McMaster University

    Graduate Student

    Erin worked at McMaster University as a Graduate Student

  • Texas A&M University

    Assistant Professor

    Department of Nutrition & Food Science

  • University of Colorado

    Postdoctoral Fellow

    I'm studying how obesity-associated changes in whole body metabolism and fuel utilization contribute to post-menopausal breast cancer.

Education

  • McMaster University

    PhD

    Medical Science

  • McMaster University

    Graduate Student



  • University of Guelph

    BSc

    Biomedical Science

Publications

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females

    Frontiers in Nutrition

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females

    Frontiers in Nutrition

  • Weight restoration on a high carbohydrate refeeding diet promotes rapid weight regain and hepatic lipid accumulation in female anorexic rats

    Nutrition & metabolism

    Refeeding a low fat diet to restore body weight in female anorexic rats caused depressed total energy expenditure (TEE) and resting energy expenditure (REE) which facilitated rapid regain. However, this weight gain was metabolically unhealthy as it resulted in elevated lipid accumulation in the liver. It is necessary to investigate the use of other diets, such as lower carbohydrate, moderate fat diets, in pre-clinical models to develop the optimal clinical refeeding diets for anorexia nervosa.

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females

    Frontiers in Nutrition

  • Weight restoration on a high carbohydrate refeeding diet promotes rapid weight regain and hepatic lipid accumulation in female anorexic rats

    Nutrition & metabolism

    Refeeding a low fat diet to restore body weight in female anorexic rats caused depressed total energy expenditure (TEE) and resting energy expenditure (REE) which facilitated rapid regain. However, this weight gain was metabolically unhealthy as it resulted in elevated lipid accumulation in the liver. It is necessary to investigate the use of other diets, such as lower carbohydrate, moderate fat diets, in pre-clinical models to develop the optimal clinical refeeding diets for anorexia nervosa.

  • Exercise Decreases Lipogenic Gene Expression in Adipose Tissue and Alters Adipocyte Cellularity during Weight Regain After Weight Loss

    Frontiers in Physiology

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females

    Frontiers in Nutrition

  • Weight restoration on a high carbohydrate refeeding diet promotes rapid weight regain and hepatic lipid accumulation in female anorexic rats

    Nutrition & metabolism

    Refeeding a low fat diet to restore body weight in female anorexic rats caused depressed total energy expenditure (TEE) and resting energy expenditure (REE) which facilitated rapid regain. However, this weight gain was metabolically unhealthy as it resulted in elevated lipid accumulation in the liver. It is necessary to investigate the use of other diets, such as lower carbohydrate, moderate fat diets, in pre-clinical models to develop the optimal clinical refeeding diets for anorexia nervosa.

  • Exercise Decreases Lipogenic Gene Expression in Adipose Tissue and Alters Adipocyte Cellularity during Weight Regain After Weight Loss

    Frontiers in Physiology

  • Ibuprofen before Exercise Does Not Prevent Cortical Bone Adaptations to Training.

    Medicine & Science in Sports & Exercise

    Ibuprofen before exercise did not prevent the skeletal benefits of exercise in that engenders higher bone strains may be required to detect an effect of ibuprofen

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females

    Frontiers in Nutrition

  • Weight restoration on a high carbohydrate refeeding diet promotes rapid weight regain and hepatic lipid accumulation in female anorexic rats

    Nutrition & metabolism

    Refeeding a low fat diet to restore body weight in female anorexic rats caused depressed total energy expenditure (TEE) and resting energy expenditure (REE) which facilitated rapid regain. However, this weight gain was metabolically unhealthy as it resulted in elevated lipid accumulation in the liver. It is necessary to investigate the use of other diets, such as lower carbohydrate, moderate fat diets, in pre-clinical models to develop the optimal clinical refeeding diets for anorexia nervosa.

  • Exercise Decreases Lipogenic Gene Expression in Adipose Tissue and Alters Adipocyte Cellularity during Weight Regain After Weight Loss

    Frontiers in Physiology

  • Ibuprofen before Exercise Does Not Prevent Cortical Bone Adaptations to Training.

    Medicine & Science in Sports & Exercise

    Ibuprofen before exercise did not prevent the skeletal benefits of exercise in that engenders higher bone strains may be required to detect an effect of ibuprofen

  • The androgen receptor supports tumor progression after the loss of ovarian function in a preclinical model of obesity and breast cancer

    Hormones and Cancer

  • Prior weight loss exacerbates the biological drive to gain weight after the loss of ovarian function

    Physiological Reports

  • Metformin accumulation correlates with organic cation transporter 2 protein expression and predicts mammary tumor regression in vivo

    Cancer Prevention Research

  • The role for adipose tissue in weight regain after weight loss

    Obesity Reviews

  • Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

    Breast Cancer Research

  • Modeling Diet-Induced Obesity with Obesity-Prone Rats: Implications for Studies in Females

    Frontiers in Nutrition

  • Weight restoration on a high carbohydrate refeeding diet promotes rapid weight regain and hepatic lipid accumulation in female anorexic rats

    Nutrition & metabolism

    Refeeding a low fat diet to restore body weight in female anorexic rats caused depressed total energy expenditure (TEE) and resting energy expenditure (REE) which facilitated rapid regain. However, this weight gain was metabolically unhealthy as it resulted in elevated lipid accumulation in the liver. It is necessary to investigate the use of other diets, such as lower carbohydrate, moderate fat diets, in pre-clinical models to develop the optimal clinical refeeding diets for anorexia nervosa.

  • Exercise Decreases Lipogenic Gene Expression in Adipose Tissue and Alters Adipocyte Cellularity during Weight Regain After Weight Loss

    Frontiers in Physiology

  • Ibuprofen before Exercise Does Not Prevent Cortical Bone Adaptations to Training.

    Medicine & Science in Sports & Exercise

    Ibuprofen before exercise did not prevent the skeletal benefits of exercise in that engenders higher bone strains may be required to detect an effect of ibuprofen

  • The androgen receptor supports tumor progression after the loss of ovarian function in a preclinical model of obesity and breast cancer

    Hormones and Cancer

  • Is regular exercise an effective strategy for weight loss maintenance?

    Physiology & Behavior

NFSC 365

3.5(2)