Resume

• 2002

  Sinhalese

  PhD

  Thesis Title: Mechanistic Studies of Hydroxylation Reactions Catalyzed by Cytochromes P450 and Diiron Monooxygenases

  Chemistry

  American Chemical Society-Member

  \nSLGSA- University of Illinois at Chicago-President (2006-2007)

  \nSLGSA-University of Illinois at Chicago-Secretary (2005-2006)

• 2000

  MSc

  Chemistry

  A/L

  Chemistry

  Physics

  Zoology

  Botany

  Devi Balika Vidyalaya. Colombo 08

• 1994

  BSc

  Chemistry

  Microbiology

  Zoology

  University of Kelaniya

• NMR

  Organic Synthesis

  LC-MS

  Gas Chromatography

  Mass Spectrometry

  Cell Culture

  NMR spectroscopy

  Organic Chemistry

  Protein Expression

  Purification

  Laboratory

  Nanoparticle preperation

  Protein Chemistry

  Chromatography

  UV/Vis

  Fluorescence Spectroscopy

  HPLC

  Spectroscopy

  Animal Models

  GC-MS

  Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles

  Cui

  Z.

  Rodriguez

  B. L.

  Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles

  The University of Texas at Austin

  University of Illinois at Chicago

  Petroleum Engineering

  Austin TX

  Surfactants development for chemically enhanced oil recovery.\nSurfactant analysis by HPLC

  Research Associate

  The University of Texas at Austin

  •\tResearch Area: Investigation of novel nucleoside analogues

  engineering nanoparticles of less than 200 nm using biocompatible materials and utilizing them as a delivery system for small molecule anti-cancer agents. \n•\tProficiently synthesized novel nucleoside analogues with enhanced anti-tumor activity as well as characterize using NMR

  mass spectrometry and HPLC techniques.\n•\tExperienced in solid lipid nanoparticles preparation with gemcitabine and cytarabine analogues and water-emulsion nanoparticles preparation with docetaxel and novel PEG conjugated Tamoxifen molecule with targeting capability. \n•\tExperienced of working with mice and cell culture techniques. \n•\tMaintained up-to-date technical expertise through literature

  technical conferences seminars and meetings.\n•\tPreparation of standard operation procedures

  maintaining Bio-safety level 2 laboratory requirements by environmental health and Safety at UT at Austin and training all new lab personal about safety protocols.\n•\tIntroduced more convenient ordering system

  routinely updated the system and ordering all the laboratory equipments and chemicals as required. \n•\tTaking responsible actions regarding chemical disposal and maintain compliance with all university regulations.\n•\tPracticing preventive maintenance on laboratory equipments

  Dell Pediatric Research Institute

  UT at Austin

  Postdoctoral Research Associate Trainee

  •\tResearch area: Analysis of metabolites of PBDEs (polybrominated diphenyl ethers) in human placenta samples.\n•\tDevelopment of analytical method to monitor and quantify PBDEs and their metabolites in human placenta samples using GC-MS spectrometry.

  University of Illinois at Chicago

  Research Assistant/ Teaching Assistant

  Research area: Mechanistic and kinetic studies of hydroxylation reactions catalyzed by Cytochromes P450 and diiron monooxygenases

  Experienced in GC

  GC-MS

  HPLC

  UV/Vis spectroscopy

  NMR

  and stopped flow laser flash photolysis

  Synthesized several enantiomerically pure compounds

  more than twenty bicyclic molecules

  isotopically labeled compounds and some small molecules with cyclopropyl ring systems. Some of them have never been synthesized before

  Experienced in protein expression and purification of various proteins including Cytochromes P450 and chloroperoxidase

  University of Illinois at Chicago

  Gemcitabine derivatives and their applications

  us

  Zhengrong Cui

  Lipophilic monophosphorylated derivatives and nanoparticles

  us

  Michael Sandoval

  Zhengrong Cui