Anne Taylor

 AnneM. Taylor

Anne M. Taylor

  • Courses1
  • Reviews4

Biography

University of North Carolina Chapel Hill - Biomedical Engineering

Chief Scientist Officer & Co-Founder of Xona Microfluidics, LLC
Research
Anne
Taylor
Durham, North Carolina
Dr. Anne Marion Taylor, Ph.D., is the Chief Scientist Officer & a co-founder of Xona Microfluidics, LLC. She was faculty at UNC-Chapel Hill for 9 years before moving her lab to Xona. At Xona, her lab continues to conduct NIH-funded research.

Xona provides to the neuroscience research community unique, disposable platforms for cellular organization and to sustain viability in vitro.  Our neuron devices and chips provide compartmentalization, fluidic isolation and improved cellular organization over traditionally chaotic neuronal cell cultures.

Xona Microfluidics offers a wide selection of devices for neuron cell culture. Our new XonaChips™ are pre-assembled and easy to use. They are especially useful for culturing human stem cell-derived neurons. The XonaChip™ offers the researcher a novel method to isolate and grow axons, ultimately delivering the ability to study neuronal response to axonal damage due to disease or injury in an isolated fluidic environment.

Xona Microfluidics distributes and supports its products directly, as well as through qualified distributors, to hundreds of research organizations in over 20 countries.

Specialties: microfluidics, micro-devices for cell-based application, neurobiology, axonal protein-synthesis, synapse development, synaptic plasticity.


Experience

  • UNC Neuroscience Center

    Primary Faculty

    www.med.unc.edu/neuroscience

  • University of North Carolina at Chapel Hill

    Faculty

    Anne worked at University of North Carolina at Chapel Hill as a Faculty

  • Caltech

    Postdoctoral Scholar

    My research involves developing and using microfluidic devices to study cellular mechanisms of synaptic plasticity. Lab of Erin Schuman.

  • UC Irvine

    Postdoctoral Scholar

    My work involved using the microfluidic platform I developed as a graduate student to isolate and characterize the mRNA population in cortical axons. Lab of Carl Cotman.

  • Xona Microfluidics, LLC

    Chief Scientist & Co-founder

    Xona provides innovative technology for experimental neuroscience.

Education

  • Washington University in St. Louis

    BS

    Engineering

  • University of California, Irvine

    Doctor of Philosophy (PhD)

    Bioengineering and Biomedical Engineering

  • UC Irvine

    Postdoctoral Scholar


    My work involved using the microfluidic platform I developed as a graduate student to isolate and characterize the mRNA population in cortical axons. Lab of Carl Cotman.

Publications

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

    Journal of Cell Biology

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

    Journal of Cell Biology

  • Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients

    Lab-on-a-Chip

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

    Journal of Cell Biology

  • Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients

    Lab-on-a-Chip

  • Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips

    Journal of Visualized Experiments

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

    Journal of Cell Biology

  • Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients

    Lab-on-a-Chip

  • Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips

    Journal of Visualized Experiments

  • Cloning SU8 silicon masters using epoxy resins to increase feature replicability and production for cell culture devices

    Biomicrofluidics

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

    Journal of Cell Biology

  • Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients

    Lab-on-a-Chip

  • Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips

    Journal of Visualized Experiments

  • Cloning SU8 silicon masters using epoxy resins to increase feature replicability and production for cell culture devices

    Biomicrofluidics

  • Magnetic alignment of microelements containing cultured neuronal networks for high-throughput screening

    Journal of Biomolecular Screening

  • Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

    Nature Communications

  • Messenger RNAs localized to distal projections of human stem cell derived neurons

    Scientific Reports

  • Multi-compartment microfluidic device geometry and covalently bound poly-D-lysine influence neuronal maturation

    Frontiers in Bioengineering and Biotechnology

  • Unique axon-to-soma signaling pathways mediate dendritic spine loss and hyper-excitability post-axotomy

    BioRxiv 642207

  • The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates

    Journal of Cell Biology

  • Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients

    Lab-on-a-Chip

  • Compartmentalization of Human Stem Cell-Derived Neurons within Pre-Assembled Plastic Microfluidic Chips

    Journal of Visualized Experiments

  • Cloning SU8 silicon masters using epoxy resins to increase feature replicability and production for cell culture devices

    Biomicrofluidics

  • Magnetic alignment of microelements containing cultured neuronal networks for high-throughput screening

    Journal of Biomolecular Screening

  • Use of pre-assembled plastic microfluidic chips for compartmentalizing primary murine neurons

    Journal of Visual Experimentation

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BMME 160

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