Resume

• 2016

  Certificate from American Chemical Society - 2 Days course on Laboratory Safety

  Key Topics learned - \n•Federal Regulatory Overview\n•OSHA’s Laboratory Safety Standard and Subpart Z

  Toxic and Hazardous Substances\n•OSHA’s “Particularly Hazardous Substances: \n•Uniform and International Building and Fire Code’s Maximum Allowable Quantities and Chemical Definitions\n•Fume Hoods and Other Ventilation Devices and Systems\n•Chemical Toxicology and Permissible Exposure Limits\n•Environmental Protection and Hazardous Waste\n•Chemical Segregation and Storage\n•Gases

  Refrigerated Chemicals

  and Cryogenics\n•Peroxide Formers and other Time Sensitive Chemicals\n•Laboratory Close-outs and Chemical Transportation\n•Safety Data Sheets and the new Globally Harmonized System (GHS) of Chemical Classification and Labeling\n•Controlled Substances and Regulated Explosives Programs\n•Cyanide Safety and First Aid\n•Hydrofluoric Acid Safety and First Aid\n•Inspections

  and Fume Hood Evaluations\n•Accidents

  Investigations

  and Spill Response\n•Laboratory Fire Safety and Response\n

  Laboratory Safety

  American Chemical Society

• 2014

  Bengali

  Hindi

  English

  Certificate

  Executive Education Training

  The Ohio State University Fisher College of Business

• 2012

  Certificate

  Management Skills for New Managers

  American Management Association

• 2004

  Indian Journal of Nuclear Medicine

  19 (3)

  98-114. The Role of Radiolabeled Peptide-Nucleic Acid Chimeras and Peptides in Imaging Oncogene Expression

  Oncogenes such as K-RAS

  CCND1

  HER2

  and c-MYC and tumor suppressor gene p53 are overexpressed in various types of cancer cells in vivo. Oncogene peptic nucleic acid and (PNA) probes were synthesized with an insulin-like growth factor 1 receptor peptide specific for the C terminus and a metal ion chelating peptide on the N terminus. Chimeric probes were purified by HPLC and characterized by matrix assisted laser desorption ionization time of flight (MALDI-TOF) mass spectrometry. Mismatch PNA sequences served as controls. K-RAS PNA chimeras inhibited cell proliferation and K-RAS protein expression of the pancreatic cell line AsPC1. PNA-chimeras were labeled with Tc-99m with 97+1.5% yields and evaluated in athymic nude mice bearing BT474\nor MCF7 human breast tumor xenografts. Significantly greater tumor uptake (P <0.05) was seen with Tc-99mPNA probes than the corresponding mismatch probes. Analogs of vasoactive intestinal peptide (VIP) specific for VPAC-1 oncogene receptor expression were similarly synthesized

  purified

  and characterized. One analog

  TP3982

  was labeled with positron emitting Cu-64. Tissue distribution of Cu-64-TP3892 in mice bearing human breast cancer T47D xenografts demonstrated enhanced tumor uptake

  which permitted unequivocal delineation of tumors by MOSAIC small animal positron emission tomographic (PET) imaging. The results demonstrate the important role of radiolabeled PNAs and peptides in imaging gene expression

  and warrant further evaluation.\n

  Indian Journal of Nuclear Medicine

  19 (3)

  98-114. The Role of Radiolabeled Peptide-Nucleic Acid Chimeras and Peptides in Imaging Oncogene Expression

  Biocidal organotin compounds: Part 1. Preparation and characterization of triorganotin(IV) 4‐pyridyl‐ and 2‐pyrimidyl‐ thioacetates and the crystal structure of triphenyltin(2‐pyrimidylthioacetate); A. Chakrabarti Sk. Kamruddin T. K. Chattopadhyaya A.

  Separation of Monoclonal Antibodies by Analytical Size Exclusion Chromatography By Atis Chakrabarti Submitted: October 25th 2016 Peer Reviewed: December 21st 2017 Published: February 21st 2018

  Cancer Biol Ther. 2007 Mar 26; 6(6). Radiohybridization PET Imaging of KRAS G12D mRNA expression in human pancreas cancer xenografts with [(64)Cu]DO3A-Peptide nucleic acid-peptide nanoparticles; Atis Chakrabarti

  Kaijun Zhang

  M R Aruva

  Wickstrom E.

  ATIS

  CHAKRABARTI

  Apex Pharmaceuticals

  Inc.

• 2000

  Thomas Jefferson University Hospitals

  University of Scranton

  Camden County College

  Tosoh Bioscience - Separations & Purification

  Chromatography

  RPC

  NPC

  HILIC

  SEC

  IEX

  Tosoh Bioscience LLC

  Tosoh Bioscience - Separations & Purification

  King of Prussia

  PA 19406

  His technical service group supports customers on TSKgel columns

  Toyopearl and TSKgel process media used for the separation of small molecules

  biopolymers and synthetic polymers.

  Technical Service Manager / Senior Applications Scientist

  Greater Philadelphia Area

  Design

  synthesis

  purification and characterization of different therapeutic PNA-Peptide Chimera probes by different modes of chromatography including SEC

  AEX

  Affinity and analytical and preparative HPLC. Probes were used for detecting pancreatic cancer gene expression using Positron Emission Tomography (PET) (Cu-64) and Scintigraphic imaging (Tc99m).

  Post Doctoral Fellow

  Thomas Jefferson University Hospitals

  King of Prussia

  PA 19406

  As a manager of the Technical Service (Laboratory Products) his group is responsible for technical support for TSKgel HPLC columns and laboratory instrumentation. His group is also involved in developing applications on TSKgel analytical chromatography columns. He leads a talented group of technical service specialists.

  Technical Service Manager (Laboratory Products)

  Tosoh Bioscience LLC

  Scranton

  Pennsylvania Area

  Taught toxicology for Masters in Science (MS)

  Adjunct Assistant Professor

  University of Scranton

  Chromatographic analysis and Method development for quality control: Analysis of cosmetics

  flavors and fragrances

  analgesic

  residual solvents using GC and HPLC; Analysis of full monographs of Vitamins

  Neutraceuticals and Dietary Supplements

  using Gas chromatography

  HPLC

  UV and USP wet chemical methods

  friability test

  dissolution testing within the framework of cGMP guidelines.

  Apex Pharmaceuticals

  Inc.

  Tosoh Bioscience LLC

  King of Prussia

  PA

  Laboratory Safety Officer

  King of Prussia

  PA

  He is covering the technical service of analytical chromatography columns and process chromatography. He leads a talented group of technical service specialists. His group is involved in developing applications on analytical chromatography TSKgel columns and process media TOYOPEARL and TSKgel resins. His technical service group supports customers working on the isolation and purification of biopolymers using all modes of chromatography.

  Manager

  Technical Service

  Tosoh Bioscience LLC

  Blackwood

  NJ

  Teaches organic chemistry and forensic toxicolgy.

  Adjunct Faculty

  Camden County College

• 1995

  Post Doctoral Fellowship

  Purified the wild type and mutant proteins by different chromatographic techniques

  characterized their folding by a number of electrophoretic and biophysical techniques including

  SDS-PAGE

  Native PAGE

  EMSA

  UV-Vis

  CD

  DSC.

  Protein Chemistry and molecular biophysics

  Indian Institute of Science

  American Chemical Society

• 1990

  Doctor of Philosophy - PhD

  Research

  Organic Chemistry

  University Of North Bengal

• Chemistry

  Protein Chemistry

  SDS-PAGE

  Purification

  Analytical Chemistry

  Biochemistry

  Laboratory

  Molecular Biology

  GMP

  UV/Vis

  UV/Vis Spectroscopy

  Protein Purification

  Pharmaceutical Industry

  Laboratory Skills

  HPLC

  Organic Chemistry

  Biotechnology

  Chromatography

  High-Performance Liquid Chromatography (HPLC)

  Cell Culture

  Biochem Soc Trans. 2007 Feb; 35 (Pt 1):72-6. Tian X

  Chakrabarti A

  Amirkhanov N

  Aruva MR

  Zhang Receptor-mediated internalization of chelator-PNA-peptide hybridization probes for radioimaging or magnetic resonance imaging of oncogene mRNAs in tumours;

  Biochem Soc Trans. 2007 Feb; 35 (Pt 1):72-6. Tian X

  Chakrabarti A

  Amirkhanov N

  Aruva MR

  Zhang Receptor-mediated internalization of chelator-PNA-peptide hybridization probes for radioimaging or magnetic resonance imaging of oncogene mRNAs in tumours;